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FLUORESCENCE CROSS-CORRELATION SPECTROSCOPY (FCCS)


Fluorescence cross- correlation spectroscopy (FCCS) extends the FCS procedure in that it looks at the correlation between different colors (cross-correlation) rather than just the same color (auto-correlation). In other words, coincident green and red intensity fluctuations correlate if green and red labeled particles are moving together. As a result, FCCS provides a highly sensitive measurement of molecular interactions independent of diffusion rate. ​

List of the Euro-BioImaging Node Candidates that offer fluorescence cross-correlation spectroscopy (FCCS) for interim operation :


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  • EMBL - Advanced Light Microscopy Node EMBL
  • Finland - Finnish ALM Node - Advanced Light Microscopy Finnish Node
  • France - France BioImaging Node
  • Netherlands - The Van Leeuwenhoek Center for Advanced Microscopy (LCAM) - Functional Imaging Flagship Node Amsterdam
  • Poland - Advanced Light Microscopy Polish Node
  • Spain - Advanced Light Microscopy Node Bilbao Spain 
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