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SELECTIVE PLANE ILLUMINATION MICROSCOPY (SPIM) 


Light sheet microscopy, often referred to as single plane illumination microscopy (SPIM), is a rapidly emerging technology that combines optical sectioning with multiple-view imaging to observe tissues and living organisms with impressive resolution. Unlike the conventional techniques of widefield and confocal fluorescence microscopy, the light sheet technique illuminates on the region surrounding the focal plane of the detection objective in a twin objective configuration.

List of the Euro-BioImaging Node Candidates that offer selective plane illumination microscopy (SPIM) for interim operation :


  • EMBL -Advanced Light Microscopy Facility, EMBL
  • Finland - Finnish ALM Node - Advanced Light Microscopy Finnish Node
  • France - France BioImaging Node
  • Italy - Advanced Light Microscopy Italian Node
  • Spain- B-Min - Mesoscopic Imaging Node Barcelona ​
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